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Drug Discov Ther ; 14(1): 58-60, 2020.
Article in English | MEDLINE | ID: covidwho-5186

ABSTRACT

The SARS-CoV-2 virus emerged in December 2019 and then spread rapidly worldwide, particularly to China, Japan, and South Korea. Scientists are endeavoring to find antivirals specific to the virus. Several drugs such as chloroquine, arbidol, remdesivir, and favipiravir are currently undergoing clinical studies to test their efficacy and safety in the treatment of coronavirus disease 2019 (COVID-19) in China; some promising results have been achieved thus far. This article summarizes agents with potential efficacy against SARS-CoV-2.


Subject(s)
Antiviral Agents/pharmacology , Betacoronavirus , Coronavirus Infections/drug therapy , Coronavirus Infections/virology , Drug Discovery , Adenosine Monophosphate/analogs & derivatives , Alanine/analogs & derivatives , Alanine/pharmacology , Amides/pharmacology , Antiviral Agents/chemistry , Betacoronavirus/drug effects , Betacoronavirus/physiology , COVID-19 , Chloroquine/pharmacology , Clinical Studies as Topic , Humans , Indoles/pharmacology , Pandemics , Pneumonia, Viral , Pyrazines/pharmacology , Ribonucleotides/pharmacology , SARS-CoV-2 , Virus Replication/drug effects , COVID-19 Drug Treatment
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